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PC/PS Lipid Microparticles contain attached phosphatidylcholine and phosphatidylserine with the phospholipid headgroups exposed and available for biological interactions. Phosphatidylserine (PS) is an anionic, intracellular phospholipid component of the cell membrane and is involved in cell signaling including apoptosis. Phosphatidylcholine (PC) is primarily an extracellular phospholipid component of cell membranes and is a key structural lipid. This item is non returnable
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HY-145405 50mg C12-200 CAS: 1220890-25-4 C12-200 is a benchmark ionizable cationic lipidoid along with helper lipids. C12-200 is commonly used for mRNA delivery. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Molecular Formula C26H52NO7P, Purity >99% LPC; may contain up to 10% of the 2-LPC isomer, Formula Weight 521.667, Synonyms: 1-oleoyl-2-hydroxy-sn-glycero-3-phosphocholine
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An ionizable cationic lipid (apparent pKa = 6.44); has been used in the generation of lipid nanoparticles (LNPs) encapsulating siRNA, mRNA, or plasmid DNA for use in vitro and in vivo; LNPs containing DLin-MC3-DMA accumulate in the muscle and non-draining lymph nodes after intramuscular administration and in the spleen after intravenous administration in mice; LNPs containing DLin-MC3-DMA and encapsulating F7 siRNA reduce hepatic and plasma Factor VII levels in mice without inducing liver toxicity
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